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Catalog / Face Care / Advanced Barrier Restore Concentrate
Fresh Batch No: Lot 24-0442 | Cleanroom Verified: Koshi Province Labs
CDerma Advanced Barrier Restore Concentrate in frosted glass dropper vial resting on limestone plinth
verified Formula No. 04 — Medical Grade

Active Potency

5% Niacinamide + Alpine Centella

biotech Lab Sealed pH 5.4 - 5.8
nest_eco_leaf Alpine Flora Solukhumbu Wild Centella
science NMC Compliant Doctor Protocol Certified
local_shipping Cold Chain Kathmandu Same-Day
Apothecary Prescription Standard • 30 ml Dropper

Centella Barrier Restore Concentrate — Doctor-Recommended Face Care for Wholesale Distribution

CDerma Nepal's flagship clinical formulation for wholesale B2B supply to pharmacies, cosmetic retailers, salons, and dermatology clinics. Manufactured in Itahari featuring 5% ultra-pure Madecassoside, wild alpine Centella Asiatica, and a 3-part bio-identical Ceramide complex (NP, AP, EOP).

summarize Clinical TL;DR / Quick Summary

CDerma Advanced Barrier Restore Concentrate is a doctor-formulated face care serum manufactured in Itahari, Nepal, designed to repair compromised skin barriers and reverse high-altitude trans-epidermal water loss (TEWL).

  • Actives: 5% Madecassoside + Ceramide Trio
  • Skin Type: Sensitive, Dry, Acne-Prone
  • Optimal pH: 5.4 - 5.8 (Physiological)
  • Standard: Cleanroom ISO Class 7
star star star star star 4.97
| 142 Clinical Evaluations | 45+ Aesthetic Clinics
Dispensing & Distribution ClassificationWholesale / Clinics

Professional Retail & Clinical Protocol Standard

Dispensed through authorized cosmetic stores, beauty retailers, licensed dermatology clinics, and hospital pharmacies across Nepal.

Ideal For Treating:
Soothing After Facials & Peels Sun Damage & Tan Relief Redness & Sensitive Skin Dryness & Damaged Skin Barrier
storefrontFind In Stores & ClinicsscienceRequest Wholesale Sample

Cosmetic stores, beauty retailers, and clinics can request wholesale onboarding kits and tester displays.

local_hospitalKathmandu, Lalitpur & Bhaktapur: Stocked at 32 certified hospital pharmacies.
domain_verificationRegional Centers: Available through authorized aesthetic & dermatology centers in Pokhara, Biratnagar, Chitwan & Butwal.
Micro-Rheology & Feel

Weightless Absorption Meets Deep Barrier Nourishment

No sticky feeling, no greasy residue, and no clogged pores. This lightweight serum sinks straight into your skin within seconds, leaving it soft, smooth, and deeply hydrated.

Fast Absorption Sinks In Within 15 Seconds
Won't Clog Pores 100% Breathable & Light
Works Great With Makeup & Sunscreen Zero Flaking / Pilling
water_drop

Dew-Lock Texture

Silky golden drops that melt into your skin instantly upon gentle touch.

Zero Sticky Thickeners
air

Natural Aroma

A gentle, clean herbal scent directly from pure fresh Himalayan centella leaf water.

100% Artificial Perfume Free
Close-up cosmetic swatches showing emulsion cream and serum drop on limestone
Laboratory Swatch No. 044: Rapid spreadability test on calibrated high-porosity slate substrate.
Proven Results in Nepal

Real Results You Can See and Feel in 28 Days

Tested with 80 Nepali men & women in Kathmandu & Patan

4-Week Visible Hydration Study

98.4%

Fast Soothing Relief

Calmed burning, itching, and redness caused by Kathmandu dust and strong mountain sun within 48 hours of use.

timer Evaluation at Day 2
-42.8%

Deep All-Day Hydration

Proven to lock in skin moisture and stop dryness from winter cold and air pollution.

water_drop Moisture Barrier Test
94.6%

Healthier, Bouncier Skin

Fewer dry flaky spots around the nose and cheeks, smoother texture, and lasting radiant glow.

verified Evaluation at Day 28
clinical_notes

Dr. Arpana Karki, MD

Consultant Dermatologist & Dermo-Surgeon

NMC Reg: 9482 / Kathmandu Skin Institute

"Patients across Kathmandu Valley experience chronic micro-inflammation stemming from winter dry inversions and heavy airborne particulate matter. CDerma's formulation No. 04 is one of the few concentrates that combines clinical 5% niacinamide without flushing fillers, balanced by authentic Himalayan-harvested centella. We recommend it post-microneedling and as everyday barrier defense."
100% Disclosure Monograph

Formula Architecture & Quantitative Potency

In alignment with our clinical ethics, every bioactive percentage is transparently declared. No proprietary filler blends or obfuscated fragrance masking.

Key Ingredient
Strength
How It Helps Your Skin
Niacinamide (Vitamin B3)
5.0%
Boosts hydration, fades dark spots and acne marks, and evens out skin tone.
Alpine Centella Asiatica Extract
3.5%
Fast soothing for redness, sunburn, facial irritation, and sensitive skin.
Ceramide Complex (NP, AP, EOP)
2.0%
Replaces natural skin lipids to repair damaged barriers and stop peeling.
Multi-Molecular Hyaluronic Acid
1.5%
Deep hydration: tiny molecules hydrate deep below, while larger ones lock water on top.
D-Panthenol (Pro-Vitamin B5)
1.0%
Softens rough texture, speeds up skin healing, and boosts bounce and elasticity.
Full INCI Technical Declaration

Aqua (Himalayan Spring Distillate), Niacinamide, Centella Asiatica Leaf Extract, Ceramide NP, Ceramide AP, Ceramide EOP, Phytosphingosine, Cholesterol, Sodium Hyaluronate (Multi-Fraction), D-Panthenol, Glycerin (Vegetable), Allantoin, Xanthan Gum, Sodium Lauroyl Lactylate, Carbomer, Phenoxyethanol, Ethylhexylglycerin.

Application Ritual & Integration

Clinical Routine Placement

Formulated as Step 3 in your restorative regimen. Safe for morning and evening post-cleanse application.

Step 01

Purify

Gentle Amino-Acid Hydrating Foam Cleanser (pH 5.5).

Step 02

Prepare

Himalayan Botanical Calming Mist or Dermal Toner.

Step 03 • Concentrated Active verified

Barrier Restore Concentrate

Dispense 3-4 drops directly onto dry fingertips. Press gently across forehead, cheeks, and neck until fully absorbed.

Step 04

Occlude & Protect

Lipid Repair Balm at night, Mineral Broad-Spectrum SPF 50 during daylight.

Nepali model comfortably applying CDerma concentrate serum in sunlit clinical bathroom
Doctor Instructions

Post-Treatment Care Protocol

For compromised skin post-microneedling, laser resurfacing, or harsh tretinoin acclimation: apply 2 drops morning and evening directly after a sterile water rinse. Avoid AHA/BHA exfoliants during the initial 7 days of barrier restoration.

schedule Consistent 28-day regimen yields permanent lipid bilayer strengthening
Inquiries & Support

Frequently Asked Clinical Questions

Have questions regarding your specific skin condition, prescription compatibility, or hospital order batching? Our pharmacological team is on standby.

Clinician Consultation Line

+977 (01) 441-2940

Sun - Fri, 9:00 AM - 6:00 PM NPT

Can this concentrate be layered with Active Retinoids and Vitamin C?

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Is this safe for acne-prone, fungal acne, and sensitive skin?

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What is the shelf-life and proper storage in Nepal's climate?

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How does cosmetic store wholesale and clinic batch ordering work?

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Bottle preview

Centella Barrier Restore Concentrate

Doctor Grade • Available In Stores & Clinics

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